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In plain English: methods are validated, instruments are calibrated, records are traceable, and results are reproducible

Herrmann W, Schorr H, Obeid R, Geisel J

Current research extrapolations suggest 1216 week treatment cycles followed by 48 week rest periods, though this is based on precautionary principle rather than evidence of receptor desensitization or tolerance development

It is important to talk to your doctor or nurse about the risks and benefits of vitamin B12 injections before receiving them.

Reviewer 2 In a similar paper Tamoxifen Activation of Cre-Recombinase Has No Persisting Effects on Adult Neurogenesis or Learning and Anxiety by Rotheneichner et al

For people with low-normal B12 levels who feel fatigue or brain fog, a course can help while the root cause is investigated