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doi: 10.1167/iovs.19-28250

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The SCN1A gene belongs to a family of genes that provide instructions for making sodium channels that transport positively charged sodium ions into cells, play a key role in a cell's ability to generate and transmit electrical signals

M.LiabeufS.KamelS.CulotM.et al

In terms of sensitivity, crystallographic screening cannot be compared to any other technique, being able to identify ligands with affinities as low as sub-nanomolar and having the compound's solubility as a limit 89

l-m , Percent labeling from metabolomics (l) and proteomics (m) at 0 h, demonstrating complete cystine labeling prior to introducing unlabeled GSH (n = 3 technical replicates from one experiment)