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Step 1: Audit Your Plate

mTORC1 inhibition via rapamycin can attenuate pyroptosis by reducing mitochondrial ROS and activating mitophagy, thereby limiting inflammasome activation

116 From the perspective of glycolysis, resveratrol can restore the glycolytic process by upregulating the expression of key enzymes (such as LDHA, HK2, and PKM2), significantly increasing lactate and ATP levels, and thus improving cellular energy metabolism

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In our study, 726 upregulated DEGs and 736 downregulated DEGs were identified in the GSE14668 and GSE96851 datasets

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