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D., Snow K., et al., Defective Endocytic Trafficking of NPC1 and NPC2 Underlying Infantile NiemannPick Type C Disease, Human Molecular Genetics 12, no

With a deeper understanding of its immune regulation and mechanisms of action, these findings have increasingly highlighted their guiding value in clinical practice

doi:10.1016/j.jenvman.2017.05.033

These challenges span from accurately identifying the right patients, to delivering therapy precisely to the liver, to safely engaging novel molecular targets, and finally, to demonstrating efficacy in rigorous trials

The capillary voltage was set in a range of 22 to 25 V, the spray voltage was between 3.00 and 4.50 kV, and a capillary temperature of 180 C was employed

* Correspondence: Qiang Fang, [email protected]