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Checkpoint inhibitors (Programmed Cell Death Protein 1/Programmed Death-Ligand 1 (PD-1/PD-L1), Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4)) are already well established in oncology, but their role in radiation-induced injury is dual

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Isothiocyanates and synthetic OSC derivatives are more chemically stable and could persist longer, raising concerns regarding selective pressure on environmental resistomes if concentrations exceed ecological no-effect thresholds (Hu et al., 2025

Adapting to insulin resistance in obesity: role of insulin secretion and clearance

The ferroptosis inducers include inhibitors targeting system Xc - (sorafenib) [55] and GPX4 (RSL3) [56], with ability to induce the accumulation of lipid peroxides [57], and directly suppressing GCL (L-buthionine sulfoximine, BSO) leading to GSH depletion [58]

Another type of MMA that does not respond to vitamin B12 treatment is called Mut . People with the Mut type of MMA have too little of the MCM enzyme